Leica Scientific Forum Heidelberg

Prof. Dr. Wendy Bickmore - 01 October 2008

MRC Human Genetics Unit
Western General Hospital
Edinburgh, UK

"Relating the Spatial Organisation of the Genome in the Nucleus to Gene Expression"

• How tight is chromatin packed in the nucleus and where are genes located
• How is the packaging of a set of genes important for development - the Hox genes - changes during early development
• Discussion of an experimental system to reposition human chromosomes in the nucleus and determination of the consequences of this on gene expression

• Leica Scientific Forum - Heidelberg Oct 2008

Brain Research Center
University of Zurich, Switzerland

"Brain Cells in the Spotlight: Imaging Neural Dynamics in Vivo"

• the application of two-photon microscopy for visualizing neural dynamics in the living brain
• the development of novel labeling and microscopy techniques for resolving neural network activity
• examples of neuronal and glial cell dynamics in the neocortex and the cerebellum

• Leica Scientific Forum - Heidelberg Jul 2008

Prof. Dr. Jason Swedlow - 13 March 2008

Welcome Trust Centre for Gene Regulation & Expression
College of Life Science
University of Dundee

"Life as a Voyeur of Cell Division"

• the development and characterization of light microscopy imaging systems for live cell analyis
• the application of live cell imaging to study the events of mitosis in cells and tissues
• the development of software tools that enable collaborative image visualization and analysis

• view webcast of 13 March 2008

Dr. Jennifer Lippincott-Schwartz - 17 Sep 2007

National Institute of Health
Cell Biology and Metabolism Branch
Bethesda, USA

"New Methodologies for Imaging Protein Transport, Turnover and Topology in Living Cells"

• Advanced GFP technology
• Photoactivatable fluorescent proteins
• Live cell imaging of protein dynamics
• Fluorescence microscopy at nanometer resolution

• view webcast of 17 Sep 2007

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